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Chemical Identification
Common Name
Bromadiolone
中文通用名
溴敌隆
IUPAC
3-[(1RS,3RS;1RS,3SR)-3-(4′-bromobiphenyl-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxycoumarin
CAS
3-[3-(4′-bromo[1,1′-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2H-1-benzopyran-2-one
CAS No.
28772-56-7
Molecular Formula
C30H23BrO4
Molecular Structure
Category
Activity
Rodenticide. To be used in tamper-proof baited traps filled with sufficient fresh bait to provide an uninterrupted supply for 10-15 days. Concentrated products should be diluted with bait material as directed by the manufacturer. May be used in permanent bait stations or used periodically. May be used outdoors, in non-food storage areas and in food processing plants, but only where food or feeds, their handling equipment or packaging materials are never open or exposed.
Pest Spectrum

Rats and mice, including those resistant to first generation anticoagulants.

Formulation
BB = Block bait
DP = Dustable powder
RG =
TP = Tracking powder
TKL =
TK = Technical Concentrate
Physical Properties
Molecular weight:527.4; Physical form:Tech. is a yellowish powder. Composition:Mixture of two diastereoisomers. Tech. grade bromadiolone is 97% pure. Melting point:200-210 °C (mixture of two diastereoisomers); Vapour pressure:0.002 mPa(20 °C); Henry constant:5.55 × 10-5 Pa m3 mol-1 (calc.); Solubility:In water 19 mg/l (20 °C). In dimethylformamide 730, ethyl acetate 25, ethanol 8.2 (all in g/l, 20 °C). Soluble in acetone; slightly soluble in chloroform; practically insoluble in diethyl ether and hexane.; Stability:Thermally stable below 200 °C.;
Toxicology
Oral:Acute oral LD50 for rats 1.125, mice 1.75, rabbits 1.00, dogs >10.0, cats >25.0 mg/kg. Percutaneous:Acute percutaneous LD50 for rabbits 1.71 mg/kg. Inhalation:LC50 0.43 mg/l. ADI:( EPA ) 0.13 mg/kg [1993].
Environmental Profile
Ecotoxicology: 
Bees:Not hazardous to bees when used as directed.Birds:Acute oral LD50 for bobwhite quail 138 mg/kg. LC50 (5 d) for mallard ducks 110 ppm.Daphnia: LC50 (48 h) 2.0 mg/l.Fish: LC50 (96 h) for rainbow trout 1.4, bluegill sunfish 3.0 mg/l. 

Environmental fate: 
Soil:Leaching behaviour is inversely related to clay and organic matter content of soils. In soil column and soil layer studies, the proportion of bromadiolone remaining in the top soil layer, using aged loamy sand soil (8.8% clay, 1.05% o.m.)
Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

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