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Chemical Identification
Common Name
Teflubenzuron
中文通用名
氟苯脲
IUPAC
1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea
CAS
N-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide
CAS No.
83121-18-0
Molecular Formula
C14H6Cl2F4N2O2
Molecular Structure
Category
Activity
Insect Growth Regulator
Insecticide
Premix
Emulsifiable concentrate, suspension concentrate. Premix Parters: butachlor;
Physical Properties
Molecular weight:381.1; Physical form:White to yellowish crystals. Melting point:222.5 °C; Vapour pressure:8 × 10-7 mPa (20 °C); Partition coefficient(n-octanol and water):logP = 4.3 (20 °C); Solubility:In water 0.019 mg/l (23 °C). In acetone 10, ethanol 1.4, dimethyl sulfoxide 66, dichloromethane 1.8, cyclohexanone 20, hexane 0.05, toluene 0.85 (all in g/l, 20 °C).; Stability:Stable for more than 2 years at room temperature. On hydrolysis, DT50 (50 °C) 5 d ( pH 7), 4 h ( pH 9).;
Toxicology
Oral:Acute oral LD50 for rats and mice >5000 mg/kg. Percutaneous:Acute percutaneous LD50 for rats >2000 mg/kg. Not irritant to skin or eyes of rabbits. Non-sensitising to skin. Inhalation:LC50 (4 h) for rats >5058 mg dust/m3. ADI:( JMPR) 0.02 mg/kg b.w. [1994].
Environmental Profile
Ecotoxicology: 
Bees:Non-toxic to bees when used at recommended rates; LD50 (topical) >1000 µg/bee.Birds:Acute oral LD50 for quail >2250 mg/kg. Dietary LC50 for quail and ducks >5000 mg/kg.Fish: LC50 (96 h) for trout and carp >500 mg/l.Other beneficial spp.:Low toxicity to predatory arthropods. 

Environmental fate: 
Animals:In rats, following oral administration, teflubenzuron and its metabolites are rapidly excreted in the faeces and urine. Three metabolites have been identified in the urine (D. Eichler et al., 6th Int. Congr. Pestic. Chem. IUPSoil: DT50 in soil 2-12 w. Microbial degradation occurs in soil, with rapid metabolism to 3,5-dichloro-2,4-difluorophenylurea as the major metabolite.Plant:Almost no uptake and no metabolism in plants.
Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

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