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Chemical Identification
Common Name
Validamycin
中文通用名
井冈霉素
IUPAC
(1R,2R,3S,4S,6R)-2,3-dihydroxy-6-hydroxymethyl-4-[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-enylamino]cyclohexyl β-D-glucopyranoside
CAS
1,5,6-trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol
CAS No.
37248-47-8
Molecular Formula
C20H35NO13
Molecular Structure
Category
Activity
Fungicide
Premix
Validamycin+Pyrimidine nucleoside
Validamycin+Hexaconazole
Validamycin+Copper sulfate
Imidacloprid+validamycin+thiosultap-monosodium
Imidacloprid+validamycin
Epoxiconazole+Validamycin
Liquid, dust.
Physical Properties
Molecular weight:497.5;Colourless, odourless, hygroscopic powder.Melting point:130-135℃ (decomp); V.p.Negligible at room temperature;Solubility Readily soluble in water. Soluble in methanol, dimethylformamide and dimethyl sulfoxide. Slightly soluble in ethanol and acetone. Sparingly soluble in diethyl ether and ethyl acetate;Stability Stable at room temperature in neutral or alkaline media, but slightly unstable in acidic media.
Toxicology
Oral Acute oral LD50 for rats and mice >20 000 mg/kg.Skin and eye Acute percutaneous LD50 for rats >5000 mg/kg. Non-irritating to skin (rabbits). Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats >5 mg/l air.
Environmental Profile
Ecotoxicology
Daphnia LC50 (24 h) for D. pulex >40 mg/l;Fish LC50 (72 h) for carp >40 mg/l.
Environmental fate
Animals In animals, cleavage to glucose and an amine residue occurs.Soil/Environment Rapid microbial degradation in soil; DT505 h.
Transport Information
Hazard Class:III(Slightly hazardous)

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