Chlorophacinone

Chlorophacinone

氯鼠酮

2-[(RS)-2-(4-chlorophenyl)-2-phenylacetyl]indan-1,3-dione

2-[(4-chlorophenyl)phenylacetyl]-1H-indene-1,3(2H)-dione

3691-35-8

C₂₃H₁₅ClO₃

Rodenticides > Indandione rodenticides

Rodenticide

Molecular weight:374.8; Physical form:Pale yellow crystals. Density:Bulk density 0.38 g/cm3 (20 °C); Melting point:140 °C; Vapour pressure:1×10-4 mPa (25 °C); pKa:3.40 (25 °C); Solubility:In water 100 mg/l (20 °C). Readily soluble in methanol, ethanol, acetone, acetic acid, ethyl acetate, benzene and oil. Slightly soluble in hexane and diethyl ether. Soluble in aqueous alkalis, with the formation of salts.; Stability:Very stable and resistant to weathering.

Tech (Rat): Oral LD₅₀ 3.15 mg/kg (1 dose/21 days). 0.005% Form (Commensal rodents): LD₅₀ 63 g/kg. (Field mouse): 0.005%-0.0075% (varies by species/application). Oral:Acute oral LD₅₀ for rats 6.26 mg/kg. Percutaneous:Non-irritating to eyes and skin. Slight absorption through the skin. Inhalation:LC₅₀(1 h) for rats 9.3 mg/l.

Ecotoxicology: Bees:Not hazardous to bees when used as recommended.Birds:LC₅₀ (30 d) for bobwhite quail 95, mallard ducks 204 ppm.Daphnia:LC₅₀ (48 h) 0.42 mg/l.Fish:LC₅₀ (96 h) for rainbow trout 0.35, bluegill sunfish 0.62 mg/l. Environmental fate: Animals:In mammals, following oral administration, 90% is eliminated in the faeces within 48 hours in the form of metabolites.Soil:Parameter ranges for four soil types: K_d (adsorption) 80-1000, K_d(desorption) 57-579; K_oc 15 556-135 976.
WATER SOLUBILITY: Insoluble.

Signal Word:CAUTION; Hazard Class:Ia (Extremely hazardous)