Clopyralid

Clopyralid

二氯吡啶酸

3,6-dichloropyridine-2-carboxylic acid
or
3,6-dichloropicolinic acid

3,6-dichloro-2-pyridinecarboxylic acid

1702-17-6

C₆H₃Cl₂NO₂

Herbicides > Pyridine herbicides
Herbicides > Aromatic acid herbicides

Herbicide

Triclopyr+clopyralid
Oxyfluorfen+Clopyralid
Nicosulfuron+Atrazine+Clopyralid
Mesotrione+Clopyralid
clopyralid+fluroxypyr+pyroxsulam
Clopyralid+Clethodim+Picloram
acetochlor+mesotrione+clopyralid
Premix Parters: sulfentrazone;

Molecular weight:192.0; Physical form:Colourless crystals. Density:1.57 (20 °C); Melting point:151-152 °C; Flash point:No flashing exhibited in ignition test; Vapour pressure:1.33 mPa (pure, 24 °C); 1.36 mPa ( tech., 25 °C); Partition coefficient(n-octanol and water):logP = -1.81 ( pH 5), -2.63 ( pH 7), -2.55 ( pH 9), 1.07 (unionised, 25 °C); pKa:2; Solubility:Pure (99.2%) 7.85 (in distilled water), 118 ( pH 5), 143 ( pH 7), 157 ( pH 9) (all in g/l, 20 °C). In acetonitrile 121, n-hexane 6, methanol 104 (all in g/kg). Forms water-soluble s; Stability:Decomposes above m.p. Stable in acidic media and to light; on hydrolysis, DT50 >30 d at pH range 5-9 (25 °C) in sterile water.;

Oral:Acute oral LD₅₀ for male rats 3738, female rats 2675 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rabbits >2000 mg/kg; a severe eye irritant, not a skin irritant. Inhalation:LC₅₀ (4 h) for rats >0.38 mg/l. Phytotoxicity:Good crop tolerance of graminaceous, cruciferous crops.

Ecotoxicology: 
Algae: EC₅₀ (96 h) for Selenastrum capricornutum, cell count 6.9, cell volume 7.3 mg/l.Bees:Non-toxic to bees. LD₅₀ (48 h, oral and contact) >100 mg/bee.Birds:Acute oral LD₅₀ for mallard ducks 1465, bobwhite quail >2000 mg/kg. Dietary LC₅₀ (5 d) for mallard ducks and bobwhite quail >4640 mg/kg diet.Daphnia: EC₅₀ (48 h) 225 mg/l. EC₅₀ (21 d) immobilisation 69, reproduction 80 mg/l; NOEC 17 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 103.5, bluegill sunfish 125.4 mg/l.Worms: LC₅₀ (14 d) for earthworms >1000 mg/kg soil.Other aquatic spp.: EC₅₀ (14 d) for Lemna gibba 89 mg/l.Other beneficial spp.:No effect on nitrification, nitrogen fixation or degradation of cellulose, starch, protein and leaf material at 1-10 ppm. 

Environmental fate:
 Animals:In rats, following oral administration, there is rapid and almost quantitative unchanged elimination in the urine.Soil:In soil, microbial degradation occurs; slow degradation occurs in sterile soil. The major product is CO₂; only traces of one other metabolite have been recorded. Aerobic soil degradation depends on initial concentration ( DT₅₀

Signal Word:DANGER; Hazard Class:Ib(Highly hazardous)