Ethofumesate

Ethofumesate

乙氧呋草黄

(RS)-2-ethoxy-2,3-dihydro-3,3-dimethylbenzofuran-5-yl methanesulfonate

2-ethoxy-2,3-dihydro-3,3-dimethyl-5-benzofuranyl methanesulfonate

26225-79-6

C₁₃H₁₈O₅S

Herbicides > Benzofuranyl alkylsulfonate herbicides

Broadleaf weeds and grass weeds.

EC = Emulsifiable concentrate
SC = Suspension concentrate (=flowable concentrate)

Ethofumesate+Desmedipham+Phenmedipham

Molecular weight:286.3; Physical form:White, crystalline solid; ( tech. is a light brown crystalline solid; mild aromatic odour). Density:1.29 (20 °C, tech.); Melting point:70-72 °C; tech., 69-71 °C; Vapour pressure:0.12 to 0.65 mPa (25 °C); Henry constant:3.7 × 10-3 to 6.8 × 10-3 Pa m3 mol-1; Partition coefficient(n-octanol and water):logP = 2.7 ( pH 6.5-7.6, 25 °C); Solubility:In water 50 mg/l (25 °C). In acetone, dichloromethane, dimethyl sulfoxide, ethyl acetate >600, toluene, p-xylene 300-600, methanol 120-150, ethanol 60-75, isopropanol 25-30, hexane 4.67 (all in g/l, 25 °C).; Stability:Stable to hydrolysis in water at pH 7 and 9. At pH 5.0, DT50 940 d, forming the hydroxy analogue. Phototransformed in water, DT50 31 h.

Oral:Acute oral LD₅₀ for rats and mice >5000 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats >2000 mg/kg. Not a skin or eye irritant. Not a skin sensitiser. Inhalation: LC₅₀ (4 h) for rats >3.97 mg/l air. Phytotoxicity:Onions, peas, beans, carrots, and cotton are tolerant to some extent.

Ecotoxicology: 
Algae: EC₅₀ 3.9 mg/l.Bees: LC₅₀ (contact and oral) >50 μg/bee.Birds:Acute oral LD₅₀ for mallard ducks >3552, bobwhite quail >8743 mg/kg. Dietary LC₅₀ (8 d) for mallard ducks >1082, bobwhite quail >839 mg/ kg Daphnia: EC₅₀ (48 h) 13.52-22.0 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 11.91-20.2, bluegill sunfish 12.37-21.2, mirror carp 10.92 mg/l.Worms: LC₅₀ 134 mg/ kg soil.Other aquatic spp.: EC₅₀ (growth) (96 h) for Crassostrea virginica (Eastern oyster) 1.7 mg/l; LC₅₀ (96 h) Mysidopsis bahia (mysid shrimp) 5.4 mg/l.Other beneficial spp.: LD₅₀ for Aleochara bilineata >1250, for Poecilus cupreus and Chrysoperla carnea >2000 g/ ha. 

Environmental fate: 
Animals:Major metabolite is the lactone or free acid form of the respective 2-oxo compound.Soil:Ethofumesate is biologically degraded in soil to transient degradates which are rapidly converted to soil-bound residues and mineralised to CO₂. Photodegradation also occurs. DT₅₀ ranges from 10-122 d (lab.) and 84-40Plant:In plants, ethofumesate is metabolised to the 2-hydroxy and 2-oxo derivatives, methanesulfonic acid, and CO₂.

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)