Fenpropidin

Fenpropidin

苯锈啶

1-[(RS)-3-(4-tert-butylphenyl)-2-methylpropyl]piperidine

1-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]piperidine

67306-00-7

C₁₉H₃₁N

Fungicides > Unclassified fungicides

Fungicide

Fenpropidin+propiconazole
Emulsifiable concentrate. 
Premix Parters: bensulfuron-methyl; propanil;

Molecular weight:273.5; Physical form:Pale yellow, odourless, slightly viscous liquid. Density:0.91 (20 °C); Flash point:156 °C; Vapour pressure:17 mPa (25 °C); Henry constant:c. 10.7 Pa m3 mol-1 (25 °C, calc.); value based on calculated solubility of neutral fenpropidin at pH 7 and 9; Partition coefficient(n-octanol and water):logP = 2.59 ( pH 7, 22 °C); pKa:10.1 ( est.), strong base; Solubility:In water 530 ( pH 7), 6.2 ( pH 9) (in g/m3, 25 °C). Completely miscible with acetone, ethanol, toluene, n-octanol, n-hexane (25 °C).; Stability:Stable at room temperature in closed container for at least 3 years. Stable to u.v. light when in aqueous solution. Stable to hydrolysis at 80 °C at pH 4, 7 and 10.;

Oral:Acute oral LD₅₀ for rats >1447 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats >4000 mg/kg. Skin and eye irritant (rabbits). Not a skin sensitiser (guinea pigs). Inhalation: LC₅₀ (4 h) for rats 1220 mg/m³ air. ADI:( JMPR) 0.03 mg/ kg b.w. [1993].

Ecotoxicology: 
Algae: E_bC₅₀ (96 h) for Microcystis aeruginosa 4.4, Scenedesmus subspicatus 0.0057, Navicula pelliculosa 0.0025 mg/l.Bees:Relatively non-toxic to bees; LD₅₀ (48 h) (oral) >0.01 mg/bee; (contact) 0.046 mg/bee.Birds:Acute oral LD₅₀ for mallard ducks 1900, pheasants 370 mg/ kg.Daphnia: LC₅₀ (48 h) 0.5 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 2.6, mirror carp 3.6, bluegill sunfish 1.9 mg/l.Worms: LC₅₀ (14 d) for earthworms >1000 mg/ kg soil.Other beneficial spp.:Moderately harmful to the predatory mite Phytoseiulus persimilis ( IOBC). 

Environmental fate: 
Animals:In rats, following oral administration, fenpropidin is rapidly absorbed, distributed, metabolised and excreted in the urine and faeces. No bioretention potential.Soil:Strongly adsorbed, K_d 43.5 (sandy loam) - 117.1 (sandy clay loam), and extensively degraded, DT₅₀ 58 (loam) - 95 (sandy loam), in soil. Fenpropidin and its metabolites have little or no tendency to lePlant:Relatively rapid and extensive degradation. In wheat, the principal metabolic pathway involves hydroxylation of the piperidine ring and oxidation of the tertiary butyl group. DT₅₀ in wheat and barley plants c. 4-11 d.

Signal Word:CAUTION; Hazard Class:II(Moderately hazardous)