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Chemical Identification
Common Name
Isoproturon
中文通用名
异丙隆
IUPAC
3-(4-isopropylphenyl)-1,1-dimethylurea
or
3-p-cumenyl-1,1-dimethylurea
CAS
N,N-dimethyl-N′-[4-(1-methylethyl)phenyl]urea
CAS No.
34123-59-6
Molecular Formula
C12H18N2O
Molecular Structure
Category
Activity
Herbicide
Premix
Tribenuron-methyl+prometryn+isoproturon
Tribenuron-methyl+isoproturon
Bensulfuron-methyl+butachlor+isoproturon
Bensulfuron-methyl+isoproturon
Thifensulfuron-methyl+isoproturon
Triasulfuron+isoproturon
Diflufenican+isoproturon
Isoproturon+Halosulfuron+Pretilachlor
Isoproturon+Clodinafop-propargyl+Flucarbazone-Na
Thiobencarb+Isoproturon
Dispersion, flowable, water dispersible granule, wettable powder. 
Premix Parters: dicamba; flupropanate;
Physical Properties
Molecular weight:206.3; Physical form:Colourless crystals. Density:1.2 (20 °C); Composition:Tech. is >98.5% pure. Melting point:158 °C; ( tech., 153-156 °C); Vapour pressure:3.15 × 10-3 mPa (20 °C); 8.1 × 10-3 mPa (25 °C); Henry constant:1.46 × 10-5 Pa m3 mol-1; Partition coefficient(n-octanol and water):logP = 2.5 (20 °C); Solubility:In water 65 mg/l (22 °C). In methanol 75, dichloromethane 63, acetone 38, benzene 5, xylol 4, n-hexane c. 0.2 (all in g/l, 20 °C).; Stability:Very stable to light, acids, and alkalis. Hydrolytically cleaved by strong alkalis on heating.
Toxicology
Oral:Acute oral LD50 for rats 1826-2417, mice 3350 mg/ kg. Percutaneous:Acute percutaneous LD50 for rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits). Inhalation: LC50 (4 h) for rats >1.95 mg/l air. Phytotoxicity:Non-phytotoxic to cereals, except durum wheats.
Environmental Profile
Ecotoxicology: 
Algae: LC50 (72 h) 0.03 mg/l.Bees:Not toxic to bees; LD50 (48 h, oral) >50->100 μg/bee.Birds:Acute oral LD50 for Japanese quail 3042-7926, pigeons >5000 mg/ kg.Daphnia: LC50 (48 h) 507 mg/l.Fish: LC50 (96 h) for golden orfe 129, bluegill sunfish >100, guppies 90, rainbow trout 37, carp 193, catfish 9 mg/l.Worms: LC50 (14 d) for Eisenia foetida >1000 mg/ kg dry artificial soil.Other beneficial spp.:A dose of up to 1.5 kg/ ha (as 'Arelon') was harmless to adult female Aleochara bilineata. 

Environmental fate: 
Animals:In rats, following oral administration, 50% is eliminated within the first 8 h, predominantly in the urine.Soil:Undergoes enzymic and microbial demethylation at the nitrogen, and hydrolysis of the phenylurea to 4-isopropylaniline. DT50 in soil 6-28 d; rate of degradation increases 3x between 10 °C and 30 °C (sandy soil) and 10x in an orgaPlant:In plants, degradation is mainly via hydroxylation of the isopropyl group to 1,1-dimethyl-3-[4-(2'-hydroxy-2'-propyl)phenyl]urea; N-dealkylation also occurs.
Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

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