Mecoprop-P

Mecoprop-P

精2甲4氯丙酸

(R)-2-(4-chloro-o-tolyloxy)propionic acid

(2R)-2-(4-chloro-2-methylphenoxy)propanoic acid

16484-77-8

C₁₀H₁₁ClO₃

Herbicides > Phenoxy herbicides

Herbicide

MCPA+dichlorprop-P+mecoprop-P
Aqueous solution (amine), emulsifiable concentrate (ester). Premix Parters: Bacillus cereus; chlormequat chloride ethephon; cyclanilide; ethephon; kinetin; prohexadione-calcium;

Molecular weight:214.6; Physical form:White crystals, with a weak intrinsic odour. Density:c. 1.31 (20 °C); Melting point:94.6-96.2 °C; ( tech., 84-91 °C); Vapour pressure:0.4 mPa (20 °C); Henry constant:1.0 × 10-4 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = 1.43 ( pH 5), 0.02 ( pH 7), -0.18 ( pH 9) (all 20 °C); pKa:3.68 (20 °C); Solubility:In water 860 mg/l ( pH 7, 20 °C). In acetone, diethyl ether, ethanol >1000, dichloromethane 968, toluene 330, hexane 9 (all in g/ kg, 20 °C).; Stability:Stable to heat, light, and stable in the range pH 3 to pH 9. Photolysis DT50 680 h ( pH 5), 1019 h ( pH 7), 415 h ( pH 9).;

Oral:Acute oral LD₅₀ for rats 1050 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rats >4000 mg/kg. Eye irritant; not a sensitiser. Inhalation:LC₅₀ (4 h) for rats >5.6 mg/l. Phytotoxicity:Slightly phytotoxic to winter rye (though this is only temporary).

Ecotoxicology: 
Algae: EC₅₀ (72 h) for Pseudokirchneriella subcapitata 270, Selenastrum capricornutum 500 mg/l.Bees:Not toxic to honeybees; LD₅₀ (48 h) >25 mg/bee (dimethylammonium salt).Birds:Acute oral LD₅₀ for quail c. 500 mg/kg. Dietary LC₅₀ for bobwhite quail >5600 mg/ kg diet (dimethylammonium salt).Daphnia: EC₅₀ (48 h) >100 mg/l; NOEC (21 d) 50 mg/l.Fish: LC₅₀ (96 h) for trout 150-220, bluegill sunfish >100 mg/l.Worms: LC₅₀ (14 d) for Eisenia foetida 494 mg/ kg soil.Other aquatic spp.: EC₅₀ (14 d) for Lemna minor 60 mg/l.Other beneficial spp.:No effect on Poecilus cupreus or Aleochara bilineata. 

Environmental fate: 
Animals:In mammals, following oral administration, mecoprop-P is predominantly eliminated as conjugates in the urine.Soil:In soil, degraded predominantly by micro-organisms to 4-chloro-2-methylphenol, followed by ring hydroxylation at the 6-position and ring opening. Soil DT₅₀ (aerobic) 3-13 d.Plant:In plants, mecoprop-P is hydroxylated at the methyl group with formation of 2-hydroxymethyl-4-chlorophenoxypropionic acid. Further metabolism to the carboxylic acid ring may also occur.WATER SOLUBILITY: Tech 1.16 g/l at 20°C

Signal Word:WARNING; Hazard Class:II(Moderately hazardous)