Fungicide, bird repellent, rodent repellent
Oral Acute oral LD50 for rats 2068, guinea pigs 100-150, rabbits 100-300 mg/kg.Skin and eye Acute percutaneous LD50 for rabbits >2000 mg/kg. Irritating to mucous membranes; highly irritating to eyes; not irritating to skin. Skin sensitiser (guinea pigs).
Ecotoxicology:
Bees:Not toxic to bees; LD50>100 mg/bee.Birds: LD50< for bobwhite quail 97 mg/kg.Daphnia: EC50(48 h) 0.048 mg/l.Fish: LC50(96 h) for rainbow trout 1.9 mg/l.Worms:LC50(7 d) 190 mg/<ABBR1107 kg soil.
Environmental fate:
Animals:Ziram, orally administered to rats, was mostly eliminated within 1-2 d, leaving 1-2% of the dose in the tissues and carcass after 7 d.Soil:In soil, aerobic DT50 42 h. Unlikely to leach.Plant:The major metabolite in plants is dimethylamine salt of dimethyldithiocarbamic acid; tetramethylthiourea, carbon disulfide and sulfur can also be formed. Dimethyldithiocarbamic acid can be present as the free acid or as the metabolic conversion products,
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