nav Searchuser
Chemical Identification
Common Name
Mefluidide
中文通用名
氟磺酰草胺
IUPAC
5′-(1,1,1-trifluoromethanesulfonamido)acet-2′,4′-xylidide
CAS
N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide
CAS No.
53780-34-0
Molecular Formula
C11H13F3N2O3S
Molecular Structure
Physical Properties
Molecular weight:310.3; Physical form:Colourless, odourless crystals. Melting point:183-185 °C; Vapour pressure:<10 mPa (25 °C); Henry constant:<1.72 × 10-2 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = 2.02 (25 °C, unionised, K. Chamberlain et al., Pestic. Sci., 47, 265 (1996)); pKa:4.6; Solubility:In water 180 mg/l (23 °C). In acetone 350, methanol 310, acetonitrile 64, ethyl acetate 50, n-octanol 17, diethyl ether 3.9, dichloromethane 2.1, benzene 0.31, xylene 0.12 (all in g/l, 23 °C).; Stability:Stable at elevated temperatures, but the acetamido moiety is hydrolysed on refluxing mefluidide in acidic or alkaline solutions; degraded in aqueous solutions exposed to u.v. radiation.;
Toxicology
Oral:Acute oral LD50 for rats >4000, mice 1920 mg/ kg. Percutaneous:Acute percutaneous LD50 for rabbits >4000 mg/kg. Mild eye irritant; non-irritating to skin (rabbits).
Environmental Profile
Ecotoxicology: 
Bees:Not toxic to bees.Birds:Acute oral LD50 for mallard ducks and bobwhite quail >4620 mg/kg. Dietary LC50 (5 d) for mallard ducks and bobwhite quail >10 000 mg/ kg diet (observFish:LC50 (96 h) for rainbow trout and bluegill sunfish >100 mg/l. 

Environmental fate: 
Animals:In mammals, following oral administration, mefluidide residues are excreted intact.Soil:Rapidly degraded in soil, DT50 <1 w. 5-Amino-2,4-dimethyltrifluoromethanesulfonanilide is found as a metabolite.
Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

Porduct NewsMore

First Australian farmer sues Monsanto, claiming Roundup caused his cancer

Glyphosate

Canada approves Bayer’s Annihilator PolyZone insecticide

Deltamethrin

Australia proposes to approve BASF's herbicide Luximax

Cinmethylin

Vive Crop Protection’s Midac FC insecticide got US approval

Imidacloprid

EFSA: Risk mitigation measures on cypermethrin

Cypermethrin

BASF launches Imtrex® Flowable fungicide for field crops in Japan

Fluxapyroxad

Glyphosate lawsuit in St. Louis delayed until February 2020

Glyphosate

BASF got French approval for Revysol fungicide

mefentrifluconazole

Corteva to transfer bensulfuron-methyl business to Kumiai Chemical

Bensulfuron-methyl

Luxembourg will ban glyphosate from 2021

Glyphosate

Related CompaniesMore

PGR Technology

Country:  SouthAfrica