-
Physical Properties
Molecular weight:422.4; Physical form:Colourless needles; ( tech., light brown solid). Melting point:235-236 °C ( decomp.); pKa: pKa1 2.4 (carboxyl), pKa2 4.6, pKa3 8.0, pKa4 >12.5 (three bases); Solubility:In water >30 g/l (20 °C). In acetic acid >30 g/l (20 °C). Practically insoluble in acetone, benzene, carbon tetrachloride, chloroform, cyclohexane, dioxane, ethanol, diethyl ether, ethyl acetate, methanol, pyridine, xylene.;
-
Toxicology
Oral:Acute oral LD50 for male rats 56.8, female rats 55.9, male mice 51.9, female mice 60.1 mg/ kg. Percutaneous:Acute percutaneous LD50 for rats >500 mg/kg. Severe eye irritant. Phytotoxicity:Damage can be caused to alfalfa, aubergines, clover, potatoes, soya beans, tobacco, and tomatoes. Excessive application produces yellow spots on rice leaves. Formulated as the benzylaminobenzenesulfonate to reduce phytotoxicity. ADI:( JMPR) 0.01 mg/ kg b.w. [1998].
-
Environmental Profile
Ecotoxicology: Daphnia:LC50 (3 h) for D. pulex >40 mg/l.Fish:LC50 (48 h) for carp >40 mg/l. Environmental fate: Animals:Almost all of 3H-blasticidin-S administered to mice was excreted in the urine and faeces within 24 h.Soil:In soil, DT50 <2 d (two soil types, o.c. 2.53%, 9.6%; moisture 42.6%, 87%, respectively; pH 6.0, 25 °C).Plant:In rice plants, cytomycin and deaminohydroxy blasticidin-S were identified as the main metabolites.
-
Transport Information
Hazard Class:O (Obsolete as pesticide, not classified)