Pencycuron

Pencycuron

戊菌隆

1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea

N-[(4-chlorophenyl)methyl]-N-cyclopentyl-N′-phenylurea

66063-05-6

C₁₉H₂₁ClN₂O

Fungicides > Urea fungicides

Fungicide

Dry seed dressing, dustable powder, flowable concentrate for seed treatment, suspension concentrate, wettable powder. 
Premix Parters: cumyluron;

Molecular weight:328.8; Physical form:Colourless, odourless crystals. Density:1.22 (20 °C); Melting point:128 °C (modification A); 132 °C (modification B); Vapour pressure:5 ×10-7 mPa (20 °C, extrapolated); Henry constant:5 × 10-7 Pa m3 mol-1 (20 °C); Partition coefficient(n-octanol and water):logP = 4.68 (20 °C); Solubility:In water 0.3 mg/l (20 °C). In dichloromethane 270, toluene 20, n-hexane 0.12 (all in g/l, 20 °C).; Stability:On hydrolysis (25 °C), DT50 280 d ( pH 4), 22 y ( pH 7), 17 y ( pH 9). Photodegrades in water and on soil surfaces.

Oral:Acute oral LD₅₀ for rats >5000 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ (24 h) for rats and mice >2000 mg/kg. Non-irritating to skin and eyes (rabbits). Not a skin sensitiser. Inhalation: LC₅₀ (4 h) for rats >268 mg/m³ air (aerosol); >5130 mg/m³ air (dust). ADI:( JMPR) 0.03 mg/ kg b.w. [1992].

Ecotoxicology: 
Algae: EC₅₀ (96 h) for Scenedesmus 0.56 mg/l.Bees:Not hazardous to bees; LD₅₀ (oral and contact) >100µg/bee.Birds: LD₅₀ for bobwhite quail >2000 mg/ kg.Daphnia: EC₅₀ (48 h) 0.27 mg/l.Fish: LC₅₀ (96 h) for rainbow trout >690 mg/l (11 °C), bluegill sunfish 127 mg/l (19 °C).Worms: LC₅₀ (14 d) >1000 mg/ kg dry soil.Other beneficial spp.:Not toxic for carabid beetles (Calathus fuscipes, Pterostichus melanarius) up to 25 kg/ha. Under practical conditions, no negative effects on soil micro-organisms.

Environmental fate: 
Animals:In rats, following oral administration, up to 74% is eliminated within 3 days in the urine and faeces, either as the unchanged material or as metabolites. Eleven metabolites have been identified (I. Ueyama et al., J. Agric. Food Chem.Soil:Leaching and adsorption behaviour in soil characterises the compound as slightly mobile. Degraded in soil very effectively in laboratory studies. Based on determined DT₅₀ values, the compound can be classified as moderately stabPlant:Degradation only to a low degree. The hydroxylated metabolites (partly as conjugates) can be considered to be the main metabolites.

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)