-
Physical Properties
Molecular weight:523.4; Physical form:White powder; (tech., off-white to buff or beige powder). Density:1.42 (25 °C, tech.); Composition:Tech. material is >91% pure. Melting point:228-232 °C ( tech.); Vapour pressure:<<0.001 mPa (20 °C, gas saturation method); Henry constant:<10-1 ( pH 5.2); <10-3 ( pH 7.4); <10-5 ( pH 9.3) (all in Pa m3 mol-1, calc.); Partition coefficient(n-octanol and water):logP = 8.5; pKa:A very weak acid which is too lipophilic to form water-soluble salts.; Solubility:In water 3.8 × 10-3 ( pH 5.2), 0.24 ( pH 7.4), 10 (pH 9.3) (all in mg/l, 20 °C). In acetone 20, chloroform 3, benzene <6 (all in mg/l, 20 °C).; Stability:Thermally (up to 50 °C) and photolytically (30 d in direct sunlight) stable. Degraded by u.v. light when in solution.;
-
Toxicology
Oral:Acute oral LD50 for male rats 0.4, male rabbits 0.2, male mice 0.4, female guinea pigs 2.8, cats c. 25, dogs 0.25-3.6 mg/kg. Percutaneous:Acute percutaneous LD50 for rabbits 0.25-0.63 mg/kg. Slight to mild skin and eye irritant (rabbits). A moderate skin sensitiser (guinea pigs), but negligible risk of sensitisation from formulated product. Inhalation: LC50 (4 h) 5 mg/l air.
-
Environmental Profile
Ecotoxicology:
Birds:Acute oral LD50 for Japanese quail 11.6, chickens 4.5, mallard ducks 0.31 mg/kg. Dietary LC50 (40 d) for mallard ducks 2.7, bobwhite quail 0.8 ppm.Daphnia: LC50 (48 h) 0.34 mg a.i./l (as formulation).Fish: LC50 (96 h) for bluegill sunfish 0.165, rainbow trout 0.051 mg/l.
Environmental fate:
Animals:In mammals, a number of hydroxycoumarins are formed.Soil:Degraded in soils ( pH 5.5 to pH 8) under aerobic and flooded conditions. Koc (average) 50 000, range 14 000-106 000; Kd 1040 (average), range 625-1320. DT
-
Transport Information
Signal Word:DANGER; Hazard Class:Ib(Highly hazardous)