Chemical Identification
Common Name
Probenazole
中文通用名
烯丙苯噻唑
IUPAC
3-allyloxy-1,2-benzothiazole 1,1-dioxide
or
3-allyloxy-1,2-benz[d]isothiazole 1,1-dioxide
CAS
3-(2-propenyloxy)-1,2-benzisothiazole 1,1-dioxide
CAS No.
27605-76-1
Molecular Formula
C10H9NO3S
Molecular Structure
Physical Properties
Form: colorless crystals. Molecular weight:223.2.Melting point 138°-139°C. Readily soluble in acetone, dimethylformamide, chloroform. Slightly soluble in benzene, diethyl ether, ethanol, methanol. Very slight solubility in hexane, ligroin.
Toxicology
Oral LD50 (Rat) 2030 mg/kg; (Mouse) 2750-3000 mg/kg. (Rat): Dermal LD50 >5000 mg/kg.Percutaneous:Acute percutaneous LD50for rats >5000 mg/ kg.
Environmental Profile
Ecotoxicology: 
Fish: LC50 (48 h) for carp 6.3, Japanese killifish >6.0 mg/l. 

Environmental fate: 
Soil:Half-life in soil <24 h (alluvial or volcanic soil).WATER SOLUBILITY: Slightly soluble in water (c. 150 mg/l) HAZARDS: Fish: LC50 (48 h) 6.3 mg/l (carp), >6 mg/l (Japanese killifish)
Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)

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