Propaquizafop

Propaquizafop

噁草酸

2-isopropylideneaminooxyethyl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate

2-[[(1-methylethylidene)amino]oxy]ethyl (2R)-2-[4-[(6-chloro-2-quinoxalinyl)oxy]phenoxy]propanoate

111479-05-1

C₂₂H₂₂ClN₃O₅

Herbicides > Phenoxy herbicides

Herbicide

Molecular weight:443.9; Physical form:Colourless crystals. Density:1.30 (20 °C); Composition:(R)- isomer. Melting point:66.3 °C; Vapour pressure:4.4×10-7 mPa (25 °C) ( OECD 104); 1.3 × 10-7 mPa (20 °C); Henry constant:9.2 × 10-8 Pa m3 mol-1 (20 °C, calc.); Partition coefficient(n-octanol and water):logP = 4.78 (25 °C); Solubility:In water 0.63 g/m3 (20 °C). In ethanol 59, acetone 730, toluene 630, n-hexane 37, n-octanol 16 (all in g/l, 25 °C).; Stability:Stable 2 y in closed container at room temperature. Moderately stable at acid and neutral pH. Rapidly hydrolysed under alkaline conditions. Stable to u.v. light.;

Oral:Acute oral LD₅₀ for rats >5000, mice 3009 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats >2000 mg/kg. Non-irritant to skin; moderate eye irritation (rabbits). No allergic sensitisation in open epicutaneous test (guinea pigs); sensitising in maximisation test. Inhalation: LC₅₀ (4 h) 2.5 mg/l air. Phytotoxicity:Occasionally soya beans and peas may show some chlorotic and necrotic spots on treated leaves at higher dosage rates; this does not affect

Ecotoxicology: 
Algae: EC₅₀ (96 h) for Selenastrum capricornutum >2.1 mg/l.Bees: LD₅₀ (48 h) (oral) >20 µg/bee; (contact) >200 µg/bee.Birds: LC₅₀ (10 d) for mallard ducks and (14 d) for bobwhite quail >6593 mg/ kg feed.Daphnia: EC₅₀ (acute) >>2 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 1.2, carp 0.19, bluegill sunfish 0.34 mg/l.Worms: LC₅₀ (14 d) >1000 mg/ kg soil. 

Environmental fate: 
Animals:Rapidly eliminated in the rat via urine and faeces, following oral administration.Soil:Fast degradation to the free acid (DT₅₀ c. 3 d) and to further metabolites. DT₅₀ (field) for parent and metabolites 15-26 d after spring application. DT₅₀ for aquatiPlant:Rapidly broken down in soya bean, sugar beet and cotton foliage to the free acid, followed by further metabolism to the quinoxaline oxyphenol. WATER SOLUBILITY: 0.6 mg/l at 25°C

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)