Chemical Identification
Common Name
Strychnine
中文通用名
马钱子碱
IUPAC
strychnidin-10-one
CAS
strychnidin-10-one
CAS No.
57-24-9
Molecular Formula
C21H22N2O2
Molecular Structure
Physical Properties
An alkaloid extracted from the seeds of Strychnos nux vomica. Molecular weight:334.4; Physical form:Colourless crystals. Melting point:270-280 °C (decomp.); >199 °C (sulfate); Solubility:In water 143 mg/l. In benzene 5.6, ethanol 6.7, chloroform 200 (all in g/l). Sparingly soluble in diethyl ether and petroleum spirit. Sulfate solubility in water 30 g/l (15 °C); soluble in ethanol.; Stability:Strychnine is a base, and forms water-soluble salts with acids: the hydrochloride, colourless prisms with 1.5-2.0 mol of water of crystallisation which are lost at 110 °C; the sulfate, colourless crystals (as pentahydrate) becoming anhydrous at 100 °C.;
Toxicology
Intensely poisonous; lethal dose to man, 30-60 mg/kg
Oral:Acute oral LD50 for rats 16 mg/kg.
Environmental Profile
WATER SOLUBILITY: Strychnine: practically insoluble. Strychnine sulfate: moderately soluble
Transport Information
Signal Word:DANGER; Hazard Class:Ib(Highly hazardous)

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