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Chemical Identification
Common Name
Carbetamide
中文通用名
双酰草胺
IUPAC
(R)-1-(ethylcarbamoyl)ethyl carbanilate
CAS
(2R)-N-ethyl-2-[[(phenylamino)carbonyl]oxy]propanamide
CAS No.
16118-49-3
Molecular Formula
C12H16N2O3
Molecular Structure
Physical Properties
Molecular weight:236.3; Physical form:Colourless crystals. Melting point:119 °C; (tech., >110 °C); Vapour pressure:Negligible (20 °C); Solubility:In water c. 3.5 g/l (20 °C). In acetone 900, dimethylformamide 1500, ethanol 850, methanol 1400, cyclohexane 0.3 (all in g/l). Stability:Stable under normal storage conditions. Soluble in acetone, methylene chloride, dimethylformamide, methanol. Insoluble in cyclohexanone, petroleum ether.
Toxicology
Oral:Acute oral LD50 for rats >2000 mg/kg, mice 1720 mg/kg, dogs 900 mg/kg. Percutaneous:Acute percutaneous LD50 for rabbits >500 mg/kg. Non-irritating to eyes (rabbits). Inhalation:LC50 (4 h) for rats >0.13 mg/l air. ADI:(JMPR) 0.03 mg/kg b.w. [1995].
Environmental Profile
Ecotoxicology: Bees:Not hazardous to bees when used as directed.Birds:Acute oral LD50 for bobwhite quail >2000 mg/kg.Daphnia: EC50 (48 h) 36.5 mg/l.Fish:LC50 (96 h) for rainbow trout and common carp >100 mg/l.Worms:LC50 600 mg/kg soil.Bee: wettable powder — nontoxic; liquid — nontoxic when used as directed. Environmental fate: Soil:Microbially degraded in soil; DT50c. 1 mo. Duration of activity at low temperatures is c. 2-3 mo. Kdranges from 0.10 (0.01% o.m., pH 6.6) to 7.92 Plant:Rapidly metabolised, leaving no residues in the plant.
Transport Information
Signal Word:CAUTION; Hazard Class:III (Slightly hazardous)

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