English 
搜索
Chemical Identification
Common Name
Bifenazate
中文通用名
联苯肼酯
IUPAC
isopropyl 3-(4-methoxybiphenyl-3-yl)carbazate
CAS
1-methylethyl 2-(4-methoxy[1,1'-biphenyl]-3-yl)hydrazinecarboxylate
CAS No.
149877-41-8
Molecular Formula
C17H20N2O3
Molecular Structure
Category
Activity
Acaricide/Miticide

Bifenazate is a contact acaricide active against all life stages of spider-, red- and grass mites, including eggs. It has a rapid knockdown effect (usually less than 3 days) and residual activity on the leaf lasting up to 4 weeks. The product’s activity is not temperature-dependant - control is not reduced at low temperatures. It doesn't control rust-, flat- or broad-mites.

Studies to date suggest bifenazate acts as a GABA (gamma-aminobutyric acid) antagonist in the peripheral nervous system at the neuromuscular synapse in insects. GABA is an amino acid present in the nervous system of insects. Bifenazate blocks the GABA-activated chloride channels, resulting in over-excitation of the peripheral nervous systems of susceptible pests. This mode of action is reported to be unique among acaricides, which suggests the product could play an important future role in mite resistance management strategies.

Bifenazate is active against mites resistant to standard and recently introduced acaricides. It is safe to predatory Stigmaeid mites (including Zetzellia mali - see ESA 2002), Phytoseid mites (Typhlodromus accidentalis, T pyri, Phytoseiulus persimilis, Amblyseius fallacis) and beneficial insects such as green lacewings (Chrysoperla carnea). Uniroyal recommends it for use in IPM programmes.

Studies at the University of Florida in the late 1990's identified a possible emergence of resistance to abamectin in two-spotted mites in strawberries; bifenazate may provide an alternative treatment.

In field trials, no phytotoxicity has been reported, even at rates much greater than those recommended.
CropUse
CropUses:
acerola, almonds, apples, apricots, atemoya, avocados, bananas, carambola, cherries, citrus, cotton, cucurbits, fruiting vegetables, guava, hops, jackfruits, key lime, kumquat, longan, lychee, mamey sapote, mangos, nectarines, okra, papaya, passion fruits, peaches, pears, peppermints, pistachios, plantain, plums, potatoes, pummelos, sapodillas, spearmints, stone fruits, strawberries, sugar apples, Tahiti lime, tea, tree nuts, vines, watermelons, wax jambu, white sapote

300-600 g ai/ha

Premix
Clofentezine+Bifenazate
Fenbutatin+Bifenazate
Bifenazate+Etoxazole
Bifenazate+Spirotetramat
Physical Properties
Molecular weight:300.4; Physical form:White, odourless crystals; ( is a beige solid). Density:1.31; Composition:Tech. is >90% . Melting point:120-124 °C; Flash point:110 °C; Vapour pressure:<1 × 10-2 (25 °C); Henry constant:1 × 10-3 Pa m3 mol-1; Partition coefficient(n-octanol and water):logP = 3.4 (25 °C, 7); Solubility:In water 3.76 /l (20 °C).; Stability:Stable for >1 y at 20 °C and 50% 50 (hydrolysis) 20 h (25 °C, 7); 50 (photolysis) 17 h (25 °C, 5).;
Toxicology
Oral:Acute oral 50 for rats >5000 /. Percutaneous:Acute percutaneous 50 for rats >2000 /kg. Not a skin sensitiser. Inhalation:50 for rats >4.4 /l. 
Environmental Profile
Ecotoxicology: 
Bees:50 (48 h, contact) 8.5 mg/bee.Birds:Acute oral 50 for bobwhite quail 1142 /kg. Dietary 50 (5 d) for bobwhite quail 2298, mallard ducks 726 / diet.Daphnia:50 (48 h) 0.50 /l.Fish:50 (96 h) for bluegill sunfish 0.58, rainbow trout 0.76 /l.Other beneficial spp.:Harmless to predacious mites such as the phytoseiids Amblyseius fallacis, Galendromus occidentalis and Zetzellia mali. 

Environmental fate: 
Animals:In animals, the product is considered of poor bioavailability, and most of the dose is excreted in the faeces. The small proportion that is absorbed undergoes oxidation to the corresponding azo compound, and hydroxylation; hydroxylated metabolites appear Soil:50 in aerobic soil c. 7 h; 50 (anaerobic) c. 80 d. Neither bifenazate nor its metabolites leached in a variety of soil types. 50 in natural water 45
Transport Information
Signal Word:CAUTION; 
Hazard Class:III(Slightly hazardous)

Porduct NewsMore

EU withdraws the approval of SDHI fungicide isopyrazam

Isopyrazam

ADAMA launches Timeline® FX, to deliver superior control and flexibility over broadleaf weeds

Pinoxaden Florasulam Fluroxypyr

Bayer's Rejuvra herbicide registered for use in California

Indaziflam

2-Bromoheptafluoropropane: A Key Intermediate of Broflanilide, a Meta-Diamide Insecticide with Huge Commercial Potential

broflanilide

AlgaPure seaweed extract flakes help farmer grow yield

Biostimulants

Pesticides terbufos and iprodione to be recommended for Rotterdam listing

Terbufos Iprodione

Argentina starts producing Rynaxypyr locally

Chlorantraniliprole

Chitosan Oligosaccharide:Zhongke Runyao to explore ways to industrialize research achievements on virus and cold resistant

Biostimulants

Gliforte, a unique glyphosate product with lower impact on environment

Glyphosate

MSU Licenses Technology to Adjuvants Plus Inc.

2,4-D

Related CompaniesMore

Shaanxi Sunger Road Bio-science Co., Ltd

Country:  China

Tribenuron Methyl+Carfentrazone-ethyl+Fluroxypyr-meptyl Florasulam+MCPA-isooctyl+fluroxypyr-meptyl Abamectin+Methoxyfenozide Thifluzamide+Azoxystrobin β-sitosterol Hexaconazole+Phenamacril Pymetrozine+Lambda-cyhalothrin Pymetrozine+Dinotefuran Spirotetramat+Pymetrozine Pyraclostrobin + Cyazofamid

SINO AGRO-CHEMICAL INDUSTRY LTD.

Country:  China

Prothioconazole Azoxystrobin Pyraclostrobin Methoxyfenozide Bifenazate Bispyribac-sodium Nicosulfuron Tebuconazole Pyribenzoxim Penoxsulam

Shandong Weifang Rainbow Chemical Co., Ltd.

Country:  China

Glufosinate-ammonium 2,4-D MCPA Dicamba Propanil Clethodim Glyphosate Captan Flumioxazin Sulfentrazone

Yingde Greatchem Chemicals Co., Ltd.

Country:  China

Folpet Desmedipham Dazomet Captan Triticonazole Ipconazole Metconazole Boscalid Thifluzamide Ethofumesate

Hebei Xingbai Agricultural Technology Co.,Ltd.

Country:  China

Emamectin benzoate Dinotefuran Spirodiclofen Fludioxonil Chlorfenapyr Boscalid Metaflumizone Cyazofamid Bifenazate Abamectin B2