EPN

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Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

EPN

中文通用名

苯硫膦

IUPAC

(RS)-(O-ethyl O-4-nitrophenyl phenylphosphonothioate)

CAS

O-ethyl O-(4-nitrophenyl) phenylphosphonothioate

CAS No.

2104-64-5

Molecular Formula

C₁₄H₁₄NO₄PS

Molecular Structure

General Product Information

Category

Insecticides > Organophosphorus insecticides

Activity

Acaricide/Miticide/Insecticide

Physical & Safety Data

Physical Properties

Molecular weight:323.3; Physical form:Yellow crystals; ( tech., dark amber liquid). Density:1.270 (20 °C); Melting point:34.5 °C; Vapour pressure:<4.1 ×10-2 mPa (23 °C); Partition coefficient(n-octanol and water):logP >5.02; Solubility:In water 0.92 ppm (24 °C). Soluble in many organic solvents, e.g. benzene, toluene, xylene, acetone, isopropanol, methanol.; Stability:Stable in neutral and acidic media, but hydrolysed by alkali to liberate p-nitrophenol; DT50 70 d ( pH 4), 22 d ( pH 7), 3.5 d (alkaline). On heating in a sealed tube, it is converted ;

Toxicology

Oral:Acute oral 50 for male rats 36, female rats 24, male mice 94.8, female mice 59.4 /. Percutaneous:Acute percutaneous 50 for male rats 2850, female rats 538 /. Phytotoxicity:Non-phytotoxic, except to some varieties of apple. ADI:() No [1967].

Environmental Profile

Ecotoxicology:
Birds:Acute oral 50 for ring-necked pheasants >165, bobwhite quail 220 /.Daphnia:50 (3 h) 0.0071 .Fish:50 (48 h) for carp 0.20 ppm. 50 for bluegill sunfish 0.37, rainbow trout 0.21 /l.

Environmental fate:
WATER SOLUBILITY: Very low
Animals:Metabolised in mammals by desulfuration and removal of p-nitrophenol, and also by reduction of the nitro group to an amino group (M. Hitchcock & S. D. Murphy, Biochem. Pharmacol., 1967, 16, 1801-1811; R. L. Chrzanowski &Soil:In paddy soil, 50 <15 d.Plant:The major metabolite is ethyl phenylphosphonic acid.

Transport Information

Signal Word:WARNING; Hazard Class:Ia(Extremely hazardous)