Chemical Identification
Common Name
Daminozide
中文通用名
丁酰肼
IUPAC
N-(dimethylamino)succinamic acid
CAS
butanedioic acid mono(2,2-dimethylhydrazide)
CAS No.
1596-84-5
Molecular Formula
C6H12N2O3
Molecular Structure
Physical Properties
Molecular weight:160.2; Physical form:Tech. is a white powder, with a faint amine-like odour. Composition:Tech. grade daminozide is >99% pure. Melting point:157-164 °C; Vapour pressure:22.7 mPa (23 °C); Partition coefficient(n-octanol and water):logP = -1.50 ( pH 5, 7 and 9, 21 °C); pKa:4.68 (20 °C); Solubility:In distilled water 100 g/ kg (25 °C). In methanol 50, acetone 25 (both in g/ kg, 25 °C). Insoluble in hydrocarbons.; Stability:No measurable hydrolysis over 30 d at pH 5, 7 and 9. Hydrolysed by acids and alkalis on heating. Solutions are slowly decomposed by light.
Toxicology
Oral:Acute oral LD50 for rats >5000 mg/kg. Percutaneous:Acute percutaneous LD50 for rabbits >5000 mg/kg. Inhalation:50 (4 h) for rats >2.1 /l air. (Rabbit): Mild eye irritation; nonirritating to skin
Environmental Profile
Ecotoxicology: 
Algae: EC50 for Chlorella 180 ppm.Bees:Not toxic to bees. LD50 >100 µg/bee (85% formulation).Birds:Dietary LC50 (8 d) for mallard ducks and bobwhite quail >10 000 mg/ kg diet.Daphnia: LC50 (96 h) 76 mg/l.Fish: LC50 (96 h) for rainbow trout 149, bluegill sunfish 423 mg/l.Worms: LC50 for earthworms >632 ppm. 
Environmental fate: 
Soil:Daminozide quickly dissipates in soil with most residues becoming bound, with some CO2 formation. In aerobic soil, half of the daminozide is no longer recoverable after 17 h. No 1,1-dimethylhydrazine (UDMH) or N-nitrosodimethylamine wePlant:Metabolites include 1,1-dimethylhydrazine.
WATER SOLUBILITY: 100 gm/l.
Transport Information
Signal Word:CAUTION; Hazard Class:III (Slightly hazardous)

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