Diuron

Diuron

敌草隆

3-(3,4-dichlorophenyl)-1,1-dimethylurea

N′-(3,4-dichlorophenyl)-N,N-dimethylurea

330-54-1

C₉H₁₀Cl₂N₂O

Herbicides > Urea herbicides

Herbicide

Paraquat+Diuron
MCPA+Ametryn+Diuron
Hexazinone+Diuron
Diuron+Thidiazuron+Ethephon
Butralin+Diuron
Flowable, granule, wettable powder. Premix Parters: imazosulfuron pyributicarb; pretilachlor.

Molecular weight:233.1. Physical form:Colourless crystals. Density:1.48; Melting point:158-159 °C; Vapour pressure:1.1×10-3 mPa (25 °C); Henry constant:7.04×10-6 Pa m3 mol-1 (); Partition coefficient(n-octanol and water):logP = 2.85(25 °C); Solubility:In water 36.4 mg/l (25 °C). In acetone 53, butyl stearate 1.4, benzene 1.2 (all in g/ kg, 27 °C). Sparingly soluble in hydrocarbons. Stability:Stable in neutral media at normal temperatures, but hydrolysed at elevated temperatures. Hydrolysed by acids and alkalis. Decomposes at 180-190 °C.

Oral:Acute oral LD₅₀ for rats 3400 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rabbits >2000 mg/kg for 80% DF. Mild eye irritant (WP formulation) (rabbits); non-irritating to intact skin (50% aqueous paste) (guinea pigs). Non-sensitising to ski.Causes eye irritation. Inhalation: LC₅₀ (4 h) for rats >5 mg/l.

Ecotoxicology: 
Bees:Not toxic to bees.Birds:Dietary LC₅₀ (8 d) for bobwhite quail 1730 mg/kg, Japanese quail >5000 mg/kg, mallard ducklings >5000 mg/kg, pheasant chicks >5000 mg/kg diet.Daphnia: LC₅₀ (48 h) 12 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 5.6, bluegill sunfish 5.9, guppies 25 mg/l. 
Environmental fate: 
Animals:In mammals, metabolism is principally by hydroxylation and dealkylation (C. Boehme & W. Ernst, Food Cosmet. Toxicol., 1965, 3, 797-802).Soil:In soil, enzymic and microbial demethylation of the nitrogen atom and hydroxylation at position 2 of the benzene ring occur. Duration of activity in soil is c. 4-8 mo, depending on soil type and humidity. Plant:In plants, diuron undergoes demethylation of the nitrogen atom and hydroxylation at position 2 of the benzene ring.WATER SOLUBILITY: 0.035 g/l at 20°C.

Signal Word:CAUTION; Hazard Class:III (Slightly hazardous)