Ecotoxicology: Birds:Acute oral
LD
50 for bobwhite quail 0.264
mg/kg.
LC
50 (5 d) for bobwhite quail 0.56
ppm; (30 d) for mallard ducklings 1.94
ppm.Daphnia:
EC
50 (48 h) 4.4 μg/l.Fish:
LC
50 (96 h) for rainbow trout 51 μg/l, bluegill sunfish 75 μg/l. Environmental fate: Animals:In rats, following oral administration, difethialone is characterised by a short half-life in blood, a longer half-life in the liver, and an essentially faecal elimination with almost complete absence of metabolism.Soil:Binds strongly to soil and would be classified as immobile; data for a range of four soil types: (adsorption)
K
d 2.3×10
5 to 2.4×10
7.