Diphacinone

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Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

Diphacinone

中文通用名

敌鼠

IUPAC

2-(diphenylacetyl)indan-1,3-dione

CAS

2-(diphenylacetyl)-1H-indene-1,3(2H)-dione

CAS No.

82-66-6

Molecular Formula

C₂₃H₁₆O₃

Molecular Structure

General Product Information

Category

Rodenticides > Indandione rodenticides

Activity

Rodenticide

Physical & Safety Data

Physical Properties

Molecular weight:340.4. Physical form:Yellow crystals; ( tech., pale yellow powder). Density:1.281; Composition:Tech. is 95% pure. Melting point:145-147 °C; Vapour pressure:1.37×10-5 mPa (25 °C, tech.); Henry constant:1.55×10-5 Pa m3 mol-1 ( calc.); pKa:Acidic, forming water-soluble alkali metal salts. Solubility:Practically insoluble in water (c. 0.3 mg/ kg). In chloroform 204, toluene 73, xylene 50, acetone 29, ethanol 2.1, heptane 1.8 (all in g/ kg). Soluble in alkalis with the formation of salts.; Stability:Stable for 14 d ( pH 6-9); hydrolysed in <24 h ( pH 4). Rapidly decomposed in water by sunlight. Decomposes at 338 °C (without boiling).

Toxicology

Oral:Acute oral LD₅₀ for rats 2.3 mg/kg, mice 340 mg/kg, rabbits 35 mg/kg, cats 14.7 mg/kg, dogs 3-7.5 mg/kg, pigs 150 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rats <200 mg/kg. Non-irritating to skin and eyes; non-sensitising to skin (guinea pigs). Inhalation: LC₅₀ (4 h) for rats <2 mg/l air (dust).

Environmental Profile

Ecotoxicology:
Birds:Acute oral LD₅₀ for mallard ducks 3158 mg/kg. A 56-day secondary poisoning trial with bait (50 mg a.i./kg) revealed no hazard to sparrow hawks under conditions lFish: LC₅₀ (96 h) for rainbow trout 2.8, bluegill sunfish 7.6, channel catfish 2.1 mg/l.
Environmental fate:
Animals:Not extensively metabolised in the rat; any metabolism mainly involves hydroxylation and conjugation.
WATER SOLUBILITY: 17 ppm.
DEGRADATION/METABOLISM: Soil half-life is approximately 10 days.

Transport Information

Signal Word:CAUTION; Hazard Class:Ia (Extremely hazardous)