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Physical Properties
Molecular weight:99.1g/mol; Physical form:Tech. forms colourless crystals. Density:0.551; Composition:Tech. is 99% pure. Melting point:86-87℃; Flash point:205℃; Vapour pressure:182 mPa (25℃); Henry constant:2.77 × 10-4 Pa m3 mol-1 (20℃); Partition coefficient(n-octanol and water):logP = 0.480 (unstated pH); pKa:5.92, weak acid; Solubility:In water 65.1 (pure), 58.2 ( pH 3), 67.8 ( pH 9) (all in g/l, 20℃). In acetone 730, dichloromethane 602, ethyl acetate 437, hexane 12.2, methanol 968, toluene 176 (all in g/l, 20℃).; Stability:Stable under alkaline conditions, and relatively stable under acidic conditions. Stable to light and heat.
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Toxicology
Oral:Acute oral LD50 for male rats 4678, female rats 3909, male mice 2148, female mice 1968 mg/ kg. Percutaneous:Acute percutaneous LD50 for male and female rats >10 000, male and female rabbits >2000 mg/kg. Irritant to eyes and mucous membranes; not irritant to skin. Inhalation: LC50 (4 h 14 d) for rats >2.47 mg/l.
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Environmental Profile
Ecotoxicology:
Algae: NOEL 29 mg/l.Bees:Not hazardous to bees. LD50 (48 h, oral and contact) >100 μg/bee. Birds:Acute oral LD50 for Japanese quail 1085, mallard ducks >2000 mg/ kg.Daphnia: EC50 (48 h) 28 mg/l.Fish: LC50 (96 h) for rainbow trout 460; LC50 (48 h) for carp 165 mg/l.Worms: LC50 (14 d) for earthworms (Eisenia foetida) >15.7 ppm.
Environmental fate:
Animals:In mammals, following oral administration, hymexazol is metabolised to glucuronides.Soil:In soil, hymexazol is degraded to 5-methyl-2-(3H)-oxazolone, DT50 2-25 d.Plant:In plants, hymexazol undergoes degradation to O- and N- glucosides.
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Transport Information
Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)