Beflubutamid

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Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

Beflubutamid

中文通用名

氟丁酰草胺

IUPAC

(RS)-N-benzyl-2-(α,α,α,4-tetrafluoro-m-tolyloxy)butyramide

CAS

2-[4-fluoro-3-(trifluoromethyl)phenoxy]-N-(phenylmethyl)butanamide

CAS No.

113614-08-7

Molecular Formula

C₁₈H₁₇F₄NO₂

Molecular Structure

General Product Information

Category

Herbicides > Amide herbicides

Activity

Herbicide.
Beflubutamid provides both pre- and post-emergence activity with early post-emergence applications (2-4 leaf stage) showing the most consistent efficacy. Certain problem weeds (e.g. Galium aparine) require early treatment. Following application, weeds exhibit signs of chlorosis. The herbicide is safe to crop at rates several times that of recommended application rate; wheat tolerates doses up to 1000 g/ha while applications to barley are safe to 500 g/ha.

CropUse

Crop uses:
barley, rye, triticale, wheat

Cereals

170-255 g ai/ha

Physical & Safety Data

Physical Properties

Molecular weight:355.3; Physical form:Fluffy white powder. Density:1.33; Composition:Tech. is >97%. Melting point:75 °C; Vapour pressure:1.1×10-2 mPa(25 °C); Henry constant:1.1×10-4 Pa m3 mol-1; Partition coefficient(n-octanol and water):logP = 4.28; Solubility:In water 3.29 mg/l (20 °C). In acetone >600, 1,2-dichloroethane >544, ethyl acetate >571, methanol >473, n-heptane 2.18, xylene 106 (all in g/l, 20 °C).; Stability:Stable at 130 °C for 5 h. Stable at pH 5, 7 and 9 for 5 d (21 °C). Fairly stable to photolysis.

Toxicology

Oral:Acute oral LD₅₀ for rats >5000 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits); not a skin sensitiser (guinea pigs). Inhalation:LD₅₀(for rats) >5 ml/l.

Environmental Profile

Ecotoxicology:
Algae:E_bC₅₀ for Selenastrum 4.45 mg/l.Bees:LD₅₀(oral and contact) >100 mg/bee.Birds:Acute oral LD₅₀ for bobwhite quail >2000 mg/kg. Dietary LC₅₀ for bobwhite quail >5200 ppm.Daphnia:Acute EC₅₀(48 h) 1.64 mg/l.Fish:LC₅₀ (96 h) for bluegill sunfish 2.69, rainbow trout 1.86 mg/l.Worms: LC₅₀(14 d) for earthworms 732 mg/kg.Other aquatic spp.:EC₅₀ for Lemna gibba 0.029 mg/l. Other beneficial spp.:Low risk to soil microflora. Environmental fate:
Low potential for mobility in soil and rapid degradation minimise potential for leaching into groundwater. Carry-over is not expected after application at approved rates.Animals:The main metabolite is the same as in soil.Soil:Soil DT₅₀ 5.4 d; the main metabolite is the corresponding butanoic acid, formed by cleavage of the amide bond; this metabolite is itself rapidly degraded in soil. K_oc 852-1793. Stable to hydrolysis atPlant:The main metabolite is the same as in soil.

Bobwhite quail	LD₅₀ >2,000 mg/kg
Bluegill sunfish _{[96 h]}	LC₅₀ 2.69 mg/L
Rainbow trout _{[96 h]}	LC₅₀ 1.86 mg/L
Daphnia_{[48 h]}	EC₅₀1.64 mg/L
Bee	LD₅₀ >100 μg/bee
Earthworm _{[14 d]}	LC₅₀ 732 mg/kg
Selenastrum	EbC₅₀4.45 μg/L
Lemna	EC₅₀0.029 mg/L

Fate in soil:
Degraded chemically and microbially in soil, soil half-life is around 4.5-118 days in laboratory aerobic degradation studies. The adsorption/desorption coefficient (K_oc) in soils is 852-1793. There is no phytoxicity to following crops.

Fate in aquatic systems:
Stable to hydrolysis at pH 5-9. In a water/sediment study, beflubutamid degrades with a DT₅₀ of 49-64 days in the water/sediment system and 16-20 days in the water phase.

Transport Information

Hazard Class:O (Obsolete as pesticide, not classified)