Isouron

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Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

Isouron

中文通用名

异噁隆

IUPAC

3-(5-tert-butyl-1,2-oxazol-3-yl)-1,1-dimethylurea
or
3-(5-tert-butylisoxazol-3-yl)-1,1-dimethylurea

CAS

N′-[5-(1,1-dimethylethyl)-3-isoxazolyl]-N,N-dimethylurea

CAS No.

55861-78-4

Molecular Formula

C₁₀H₁₇N₃O₂

Molecular Structure

General Product Information

Category

Herbicides > Urea herbicides
Herbicides > Oxazole herbicides

Activity

Herbicide

Physical & Safety Data

Physical Properties

Molecular weight:211.3; Physical form:Colourless crystals. Density:1.23; Melting point:119-120 °C; Flash point:156 °C (seta flash tester); Vapour pressure:0.051 mPa (25 °C); Partition coefficient(n-octanol and water):logP = 1.98; Solubility:In water 300 mg/l (25 °C). In ethanol 357, acetone 270, xylene 240 (all in g/l, 25 °C).; Stability:Stable in sunlight, but decomposed slowly in aqueous solution.

Toxicology

Oral:Acute oral LD₅₀ for male rats 630, female rats 760, male mice 520, female mice 530 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for male and female rats >5000 mg/kg. Non-irritating to skin; slight eye irritant (rabbits). Inhalation: LC₅₀ (8 h) for rats >0.415 mg/l. ADI:0.0062 mg/ kg b.w.

Environmental Profile

Ecotoxicology:
Bees:Acute oral LC₅₀ (72 h) for honeybees 1600 mg a.i./ kg (50% WP).Birds:Acute oral LD₅₀ for bobwhite quail >2000 mg/ kg.Daphnia: LC₅₀ (3 h) for D. pulex 40 ppm.Fish: LC₅₀ (48 h) for carp 75, Japanese killifish 173 mg/l; (96 h) for bluegill sunfish c. 140, rainbow trout 110-140 mg/l.

Environmental fate:
Animals:Following oral administration, excreted in urine and faeces within 48 h.Soil:Some microbial degradation occurs in soil. DT₅₀ in soil c. 22 d. Plant:Metabolised in plants by two major degradation pathways, N-demethylation or hydroxylation of the tert-butyl group.

Transport Information

Hazard Class:III(Slightly hazardous)