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Chemical Identification
Common Name
Isoxathion
中文通用名
噁唑磷
IUPAC
O,O-diethyl O-5-phenyl-1,2-oxazol-3-yl phosphorothioate
CAS
O,O-diethyl O-(5-phenyl-3-isoxazolyl) phosphorothioate
CAS No.
18854-01-8
Molecular Formula
C13H16NO4PS
Molecular Structure
Physical Properties
Molecular weight:313.3; Physical form:Pale yellow liquid, with an ester-like odour. Density:c. 1.23; Composition:Tech. is >93%. Flash point:210 °C; Vapour pressure:<0.133 mPa (25 °C); Henry constant:<2.19 × 10-2 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = 3.88 ( pH 6.3); Solubility:In water 1.9 mg/l (25 °C). Readily soluble in organic solvents.; Stability:Unstable to alkalis. Decomposes at 160 °C.
Toxicology
Oral:Acute oral LD50 for male rats 242, female rats 180, male mice 112, female mice 137 mg/ kg. Percutaneous:Acute percutaneous LD50 for rats >2000 mg/kg. Not irritant to skin. Inhalation: LC50 (4 h) for male rats 4.2, female rats 2.0 g/m3.
Environmental Profile
Ecotoxicology: 
Bees: LC50 (contact) 0.082 μg/bee.Birds: LD50 for 7-day-old chickens 21.6, 50-day-old chickens 19.0 mg/ kg.Daphnia: LC50 (3 h) for D. pulex 0.0052 mg/l.Fish: LC50 (48 h) for carp 1.7 mg/l. 

Environmental fate: 
Soil: DT50 in soil 3-7 d.
Transport Information
Signal Word:WARNING; Hazard Class:Ib(Highly hazardous)

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