Metalaxyl

Metalaxyl

甲霜灵

methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate

methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-DL-alaninate

57837-19-1

C₁₅H₂₁NO₄

Fungicides > Anilide fungicides
Fungicides > Amide fungicides

Fungicide

Trifloxystrobin+metalaxyl+triadimenol
Thiram+metalaxyl
Thiamethoxam+metalaxyl-M
Thiamethoxam+fludioxonil+metalaxyl-M
Thiamethoxam+fludioxonil+metalaxyl-M
thiamethoxam+difenoconazole+metalaxyl-M+sedaxane+fludioxonil
Thiamethoxam+difenoconazole+metalaxyl-M
Thiamethoxam+difenoconazole+fludioxonil+metalaxyl-M
Thiamethoxam+azoxystrobin+fludioxonil+metalaxyl-M
Thiamethoxam+abamectin+azoxystrobin+fludioxonil+metalaxyl-M
Thiabendazole+Fludioxonil+Metalaxyl-M
tebuconazole+prothioconazole+metalaxyl+imidacloprid
Tebuconazole+Prothioconazole+Metalaxyl
Spinosad+thiamethoxam+R-metalaxyl+fludioxonil+azoxystrobin
sedaxane+fludioxonil+metalaxyl-M
R-metalaxyl+myclobutanil
R-metalaxyl+fludioxonil+azoxystrobin+thiabendazole
Pyraclostrobin+Metalaxyl-M
Pyraclostrobin+metalaxyl+triticonazole
Pyraclostrobin+metalaxyl+fluxapyroxad
Pyraclostrobin+metalaxyl
Propamocarb hydrochloride+Metalaxyl-M
Metalaxyl-M+Tebuconazole+Azoxystrobin
Metalaxyl-M+Propineb
Metalaxyl-M+Prochloraz+Clothianidin
Metalaxyl-M+mancozeb
Metalaxyl-M+Fludioxonil+Triticonazole
Metalaxyl-M+Fludioxonil
Metalaxyl-M+Fludioxonil
Metalaxyl-M+Cuprous oxide
Metalaxyl-M+azoxystrobin
Metalaxyl+sulfur
Metalaxyl+mancozeb
Metalaxyl+Cuprous Oxide
Metalaxyl+copper succinate
Metalaxyl+Carboxin+Ipconazole
Imidacloprid+metalaxyl+tebuconazole
Imidacloprid+metalaxyl
Imidacloprid+ipconazole+metalaxyl
Imidacloprid+imazalil+metalaxyl+tebuconazole
Imidacloprid+carboxin+metalaxyl
Hymexazol+metalaxyl
Flumorph+Metalaxyl-M
Dimethomorph+Metalaxyl
difenoconazole+metalaxyl-M+sedaxane+fludioxonil
Cymoxanil+metalaxyl
Clothianidin+metalaxyl+prothioconazole+tebuconazole
Clothianidin+ipconazole+metalaxyl
Clothianidin+carboxin+metalaxyl+trifloxystrobin
Chlorothalonil+metalaxyl-M
Chlorothalonil+metalaxyl
Azoxystrobin+metalaxyl-M
Azoxystrobin+metalaxyl+thiophanate-methyl
Azoxystrobin+Metalaxyl+Tebuconazole
Azoxystrobin+metalaxyl
Azoxystrobin+fludioxonil+metalaxyl-M+thiabendazole+thiamethoxam
Azoxystrobin+fludioxonil+metalaxyl-M+thiabendazole
Azoxystrobin+fludioxonil+metalaxyl-M
Emulsifiable concentrate, granule, flowable, wettable powder. 
Premix Parters: chlorpyrifos alpha-cypermethrin ethofumesate; ethofumesate; ethofumesate phenmedipham; lenacil;

Molecular weight:279.3; Physical form:Fine, white powder. Density:1.20 at 20 °C; Melting point:Tech. 63.5-72.3 °C; Vapour pressure:0.75 mPa (25 °C); Henry constant:1.6 × 10-5 Pa m3 mol-1 (calc.); Partition coefficient(n-octanol and water):logP = 1.75 (25 °C); pKa:<<0; Solubility:In water 8.4 g/l (22 °C). In ethanol 400, acetone 450, toluene 340, n-hexane 11, n-octanol 68 (all in g/l, 25 °C).; Stability:Stable up to 300 °C. Stable in neutral and acidic media at room temperature; on hydrolysis, DT50 ( calc.) (20 °C) >200 d ( pH 1), 115 d ( pH 9), 12 d ( pH 10).;

Oral:Acute oral LD₅₀ for rats 633, mice 788, rabbits 697 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rats >3100 mg/kg. Slight irritant to eyes; not irritant to skin of rabbits. No skin sensitisation (guinea pigs). Inhalation:50 (4 h) for rats >3600 mg/m³.

Ecotoxicology: Algae: IC₅₀ (5 d) for Scenedesmus subspicatus 33 mg/l.Bees:Not toxic to bees. LD₅₀ (48 h) (contact) >200 mg/bee; (oral) 269.3 mg/bee.Birds: LD₅₀ for Japanese quail (7 d) 923, mallard ducks (8 d) 1466 mg/kg. LC₅₀ (8 d) for Japanese quail, bobwhite quail and mallard ducks >10 000 mg/ kg.Daphnia: LC₅₀ (48 h) >28 mg/l.Fish: LC₅₀ (96 h) for rainbow trout, carp, and bluegill sunfish >100 mg/l.Worms: LC₅₀ (14 d) for Eisenia foetida >1000 mg/ kg soil.Other aquatic spp.: EC₅₀ (96 h) for mysid shrimp (Mysidopsis bahia) 25, Eastern oyster (Crassostrea virginica) 4.6 mg/l.Other beneficial spp.:Harmless to Poecilus cupreus and Coccinella septempunctata (IOBC). Environmental fate: Animals:In mammals, following oral administration, metalaxyl is rapidly absorbed and also rapidly and almost completely eliminated with urine and faeces. Metabolism proceeds via hydrolysis of the ester bond, oxidation of the 2-(6)-methyl group and of the phenyl rSoil:In soil, DT₅₀ 29 d (realistic range 10-40 d), K_oc 70 ml/g (realistic range 30-300 ml/g). DT₅₀ in water 22-48 d. Photolytically stable in water.Plant:Metalaxyl is metabolised by more than 4 types of phase I reaction to form eight metabolites; at phase II, most of the metabolites are sugar conjugated.

Signal Word:CAUTION; Hazard Class:III(Slightly hazardous)