Profenofos

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Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

Profenofos

中文通用名

丙溴磷

IUPAC

(RS)-(O-4-bromo-2-chlorophenyl O-ethyl S-propyl phosphorothioate)

CAS

O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate

CAS No.

41198-08-7

Molecular Formula

C₁₁H₁₅BrClO₃PS

Molecular Structure

General Product Information

Category

Insecticides > Organophosphorus insecticides

Activity

Acaricide/Miticide

Premix

Profenofos+phoxim
Profenofos+Lufenuron
Profenofos+lambda-cyhalothrin
Profenofos+fenvalerate
Profenofos+beta-cypermethrin
Cypermethrin+profenofos
Emulsifiable concentrate.
Premix Parters: chlorothalonil; fenamidone; fluopicolide; mancozeb;

Physical & Safety Data

Physical Properties

Molecular weight:373.6; Physical form:Pale yellow liquid, with a garlic-like odour. Density:1.455 (20 °C) (OECD 109); Composition:Tech. is 98%. Flash point:124 °C (EEC A9); Vapour pressure:1.24 ×10-1 mPa (25 °C) (OECD 104); Henry constant:1.65 × 10-3 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = 4.44 (OECD 107).; pKa:No dissociation constant between pKa 0.6 to 12; Solubility:In water 28 mg/l (25 °C). Readily miscible with most organic solvents.; Stability:Relatively stable under neutral and slightly acidic conditions. Unstable under alkaline conditions; on hydrolysis, DT50 ( calc.) (20 °C) 93 d ( pH 5), 14.6 d ( pH 7), 5.7 h.;

Toxicology

Oral:Acute oral LD₅₀ for rats 358, rabbits 700 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats c. 3300, rabbits 472 mg/kg. Non-irritant to the skin and eyes of rabbits. Inhalation: LC₅₀ (4 h) for rats c. 3 mg/l air. Phytotoxicity:Slight reddening of cotton may occur.

Environmental Profile

Ecotoxicology:
Algae:Toxic to algae.Bees:Toxic to bees.Birds:LC₅₀ (8 d) for bobwhite quail 70-200, Japanese quail >1000, mallard ducks 150-612 ppm.Fish:LC₅₀ (96 h) for rainbow trout 0.08, crucian carp 0.09, bluegill sunfish 0.3 mg/l.Worms:Practically non-toxic to earthworms.Other aquatic spp.:Highly toxic to crustaceans.

Environmental fate:
Animals:Rats rapidly excrete ¹⁴C-profenofos after oral administration. The predominant metabolic pathway involves stepwise dealkylation and hydrolysis, followed by conjugation.Soil:Mean half-life in soil (lab. and field) is c. 1 week.Plant:In cotton, Brussels sprouts and lettuce, the compound is rapidly taken up and metabolised. The overall metabolic pattern indicates degradation to polar metabolites. WATER SOLUBILITY: 20 ppm

Transport Information

Signal Word:WARNING; Hazard Class:II(Moderately hazardous)