Halofenozide

Favorites

Chemical Identification | General Product Information | Physical & Safety Data

Chemical Identification

Common Name

Halofenozide

中文通用名

氯虫酰肼

IUPAC

N-tert-butyl-N′-(4-chlorobenzoyl)benzohydrazide

CAS

4-chlorobenzoic acid 2-benzoyl-2-(1,1-dimethylethyl)hydrazide

CAS No.

112226-61-6

Molecular Formula

C₁₈H₁₉ClN₂O₂

Molecular Structure

General Product Information

Category

Insecticides > Insect growth regulators

Activity

Insecticide
Halofenozide is active against larval stages of Coleoptera, Lepidoptera and some dipteran and homopteran species. It is primarily a stomach poison. The product also has some ovicidal activity. Applications to adults cause a marked reduction in fecundity.

Halofenozide is for application to soil. It is root-systemic. Pests cease feeding within a few hours of treatment and death follows in 1-21 days depending on species.

A study conducted in adult female mealworms showed that RH-0345 increased the amount of ecdysteroids (insect moulting hormone) in the ovaries and affected reproduction.

CropUse

CropUses:
turf

Turf	184-367 g ai/ha

Physical & Safety Data

Physical Properties

Molecular weight:330.8; Physical form:White solid. Density:0.38; Melting point:>200℃; Vapour pressure:<1.3 × 10-2 mPa (25℃); Henry constant:<7.12 × 10-5 Pa m3 mol-1 ( calc.); Partition coefficient(n-octanol and water):logP = 3.22; Solubility:In water 12.3 ppm (25℃). In isopropanol 3.1%, cyclohexanone 15.4%, aromatic solvents 0.01-1%.; Stability:Stable to heat, light and water; hydrolysis DT50 310 d ( pH 5), 481 d ( pH 7), 226 d ( pH 9).

Toxicology

Oral:Acute oral LD₅₀ for rats 2850, mice 2214 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats and rabbits >2000 mg/ kg (limit dose). Moderately irritating to eyes; not irritating to skin (rabbits). Skin sensitiser (guinea pigs) for tech. Inhalation: LC₅₀ for rats >2.7 mg/l.

Environmental Profile

Ecotoxicology:
Algae: EC₅₀ 0.82 mgl.Bees: LD₅₀ (contact) >100 μg/bee.Birds:Acute oral LD₅₀ for quail >2250 mg/kg. Acute dietary LC₅₀ for quail 4522, mallard ducks >5000 ppm.Daphnia: LC₅₀ 3.6 mg/l.Fish: LC₅₀ for bluegill sunfish >8.4, trout >8.6, sheepshead minnow >8.8 mg/l.Worms: LC₅₀ >980 mg/ kg.Other aquatic spp.: EC₅₀ for shrimps 3.7, molluscs 1.2 mg/l.

Environmental fate:
Soil:Pond water photolysis DT₅₀ 10 d. Aerobic DT₅₀ (lab.) 54-468 d (9 soils), 340-845 d (3 sandy loam soils); soil dissipation DT₅₀ (field) 42-267 d (5 sites).

Transport Information

Hazard Class:O (Obsolete as pesticide, not classified)