Ipconazole

Ipconazole

种菌唑

(1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol

2-[(4-chlorophenyl)methyl]-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol

125225-28-7

C₁₈H₂₄ClN₃O

Fungicides > Triazole fungicides

Fungicide

Metalaxyl+Carboxin+Ipconazole
Ipconazole+imazalil
Imidacloprid+ipconazole+metalaxyl
Clothianidin+ipconazole+metalaxyl

Molecular weight:333.9; Physical form:Colourless crystals. Composition:The common name ipconazole refers to a mixture of the (1RS,2SR,5RS) isomer pair (I) (hydroxy, benzyl and isopropyl groups on the same side of the cyclopentyl ring) and the (1RS,2SR,5SR) isomer pair (II Melting point:88-90 °C; Vapour pressure:3.58 ×10-3 mPa (25 °C) (isomer pair I); 6.99 ×10-3 mPa (25 °C) (isomer pair II); Partition coefficient(n-octanol and water):logP = 4.21 (25 °C); Solubility:In water 6.93 mg/l (20 °C).; Stability:Good thermal and hydrolytic stability.

Oral:Acute oral LD₅₀ for rats 1338 mg/ kg. Percutaneous:Acute percutaneous LD₅₀ for rats >2000 mg/kg. Not irritating to skin; slightly irritant to eyes (rabbits). Not a skin sensitiser.

Ecotoxicology: 
Fish: LC₅₀ (48 h) for carp 2.5 mg/l.Other aquatic spp.: LC₅₀ (3 h) for Moina macrocopa >40 mg/l. 

Environmental fate: 
Animals:Metabolites in the rat are 2-(4-chlorobenzyl)-5-(1-hydroxy-1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol, 2-(4-chlorobenzyl)-5-(2-hydroxy-1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol and 1,2,4-triazole.

Hazard Class:O (Obsolete as pesticide, not classified)