Desmedipham

Desmedipham

甜菜安

ethyl 3-phenylcarbamoyloxycarbanilate

ethyl [3-[[(phenylamino)carbonyl]oxy]phenyl]carbamate

13684-56-5

C₁₆H₁₆N₂O₄

Herbicides > Carbanilate herbicides

Herbicide

Ethofumesate+Desmedipham+Phenmedipham
Emulsifiable concentrate. Premix Parters: atrazine; bentazone; bromoxynil mecoprop; carfentrazone-ethyl 2,4-D mecoprop-P; carfentrazone-ethyl MCPA mecoprop-P; clopyralid 2,4-D; 2,4-D; 2,4-D dichlorprop; 2,4-D fluroxypyr; 2,4-D MCPA; 2,4-D mecoprop; 2,4-D mecoprop MSMA; 2,4-D mecoprop-P; 2,4-D mecoprop-P sulfentrazone; 2,4-D metsulfuron-methyl; 2,4-D picloram; 2,4-D quinclorac sulfentrazone; dichlorprop ioxynil; dichlorprop-P MCPA; diflufenzopyr; diflufenzopyr nicosulfuron; glyphosate; imazethapyr; ioxynil mecoprop; karbutilate; MCPA; MCPA mecoprop; MCPA triclopyr; mecoprop; mecoprop-P; primisulfuron-methyl; triasulfuron.

Molecular weight:300.3. Physical form:Colourless crystals. Density:Pour 0.536, tap 0.620; Composition:Tech. grade is c. 97.5% pure. Melting point:120 °C. Vapour pressure:4×10-5 mPa (25 °C); Partition coefficient(n-octanol and water):logP = 3.39 ( pH 5.9); Solubility:In water 7 mg/l ( pH 7, 20 °C). Readily soluble in polar organic solvents, e.g. acetone 400, isophorone 400, methanol 180, ethyl acetate 149, chloroform 80, dichloroethane 17.8, benzene 1.6, toluene 1.2, hexane 0.5 (all in; Stability:Stable in aqueous acidic media, but hydrolysed in neutral and alkaline media. Stable for 2 years at 70 °C; DT50 224 h in aq. solution at pH 3.8 exposed to light 280 nm.

Oral:Acute oral LD₅₀ for rats >10 250, mice >5000 mg/kg. Percutaneous:Acute percutaneous LD₅₀ for rabbits >4000 mg/kg. Not a skin sensitiser. Inhalation: LC₅₀ (4 h) for rats >7.4 mg/l. Phytotoxicity:Non-phytotoxic to beet crops. ADI:( JMPR) 0.0003 mg/kg b.w. for sum of demeton-S-methyl, demeton-S-methylsulphon and oxydemeton-methyl [1989].  Be

Ecotoxicology: 
Algae: IC₅₀ (72 h) 0.061 mg/l.Bees:Not toxic to bees; LD₅₀ >50 µg/bee.Birds: LC₅₀ (14 d) for bobwhite quail and mallard ducks >2000 mg/kg. Dietary LC₅₀ (8 d) for bobwhite quail and mallard ducks >5000 mg/kg diet.Daphnia: LC₅₀ (48 h) 1.88 mg/l.Fish: LC₅₀ (96 h) for rainbow trout 1.7, bluegill sunfish 3.2 mg/l.Worms: LC₅₀ (14 d) 466.5 mg/kg dry soil. 
Environmental fate: 
Animals:In mammals, following oral administration, 80% of the parent compound and its metabolites are eliminated in the urine within 24 hours. Hydrolysis to ethyl N-(3-hydroxyphenyl)carbamate (EHPC) and conjugation (to glucuronides and ethereal sulfates)Soil: DT₅₀ in soil c. 34 d, DT₉₀ <115 d, with formation of ethyl 3-hydroxycarbanilate, which undergoes further degradation. Therefore, desmedipham does not accumulate in soil, nor is there any relevant uptake by foPlant:In sugar beet, EHPC is the major metabolite, with m-aminophenol as a further metabolite.
WATER SOLUBILITY: 7 mg/l at 20° C (pH 7)

Signal Word:WARNING; Hazard Class:II (Moderately hazardous)